Chang Y-W, Tsai S-J, Yang AC. Development of an Al-based Web Diagnostic System for Phenotyping Psychiatric Disorders. Frontiers in Psychiatry. 2020;11:1060. [Link]
Furutani N, Nariya Y, Takahashi T, Noto S, Yang AC, Hirosawa T, et al. Decomposed Temporal Complexity Analysis of Neural Oscillations and Machine Learning Applied to Alzheimer’s Disease Diagnosis. Frontiers in psychiatry. 2020;11:911. [Link]
Hsu CF, Chao H-H, Yang AC, Yeh C-W, Hsu L, Chi S. Discrimination of Severity of Alzheimer’s Disease with Multiscale Entropy Analysis of EEG Dynamics. Applied Sciences. 2020;10(4):1244. [Link]
Lin C-Y, Tsai S-J, Peng C-K, Yang AC. Sleep state instabilities in patients with periodic limb movements in sleep-Detection and quantification with heart rate variability. Psychiatry research. 2020;293:113454. [Link]
Lin E, Kuo P-H, Liu Y-L, Yu YW-Y, Yang AC, Tsai S-J. Prediction of Antidepressant Treatment Response and Remission Using an Ensemble Machine Learning Framework. Pharmaceuticals. 2020;13(10):305. [Link]
Rolls ET, Cheng W, Gilson M, Gong W, Deco G, Lo C-YZ, Yang AC, Tsai S-J, Liu M-E, Lin C-P, Feng J. Beyond the disconnectivity hypothesis of schizophrenia. Cerebral Cortex. 2020;30(3):1213-33. [Link]
Ruan H, Luo Q, Palaniyappan L, Lu W, Huang C-C, Lo C-YZ, Yang AC, Liu M-E, Tsai S-J, Lin C-P, Feng J. Topographic diversity of structural connectivity in schizophrenia. Schizophrenia Research. 2020;215:181-9. [Link]
Ting EY-C, Yang AC, Tsai S-J. Role of Interleukin-6 in Depressive Disorder. International Journal of Molecular Sciences. 2020;21(6):2194. [Link]
Tsai H, Kuo TB, Yang AC, Tsai SJ, Yang CC. Difficulty in initiating sleep is associated with poor morning cardiovascular function. Psychiatry research. 2020:113518. [Link]
Yang AC. Validating the Enlarged Kyd Canon: a New Approach. ANQ: A Quarterly Journal of Short Articles,Notes and Reviews. 2020;33(2-3):189-97. [Link]
Yang AC, Jann K, Michel CM, Wang DJ. Advances in Multi-Scale Analysis of Brain Complexity. Frontiers in Neuroscience. 2020;14. [Link]
Yu Z, Qin J, Xiong X, Xu F, Wang J, Hou F, Yang AC. Abnormal topology of brain functional networks in unipolar depression and bipolar disorder using optimal graph thresholding. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2020;96:109758. [Link]
Zhang L, Ni H, Yu Z, Wang J, Qin J, Hou F, Yang AC. Investigation on the Alteration of Brain Functional Network and Its Role in the Identification of Mild Cognitive Impairment. Frontiers in neuroscience. 2020;14:1027. [Link]
2019
Chen J, Liu C, Peng CK, Fuh JL, Hou F, Yang AC. Topological reorganization of EEG functional network is associated with the severity and cognitive impairment in Alzheimer’s disease. Physica A: Statistical Mechanics and its Applications 513, 588-597 (2019)[PDF]
Chang YW, Tsai SJ, Yang AC. Development of an AI-based web diagnostic system for phenotyping psychiatric disorders. Schizophrenia Bulletin45, S226-S226 (2019) [Abstract]
Yang AC, Tsai SJ. Explainable deep learning of neuroimaging reveals key structural deficits in schizophrenia. Schizophrenia Bulletin45, S206-S206 (2019) [Abstract]
Hsu YY, Yang AC. Identifying key voxels in schizophrenia that are correlated with age of onset and duration of illness. Schizophrenia Bulletin45, S232-S232 (2019) [Abstract]
Yang AC. Validating the enlarged kyd canon: a new approach. ANQ: A Quarterly Journal of Short Articles, Notes and Reviews, 1-9 (2019) [Introduction]
2018
Yang AC*, Peng CK, Huang NE. Causal decomposition in the mutual causation system. Nature Communications 9:3378 (2018). [PDF]
Yang AC*, Tsai SJ, Lin CP, Peng CK, Huang NE. Frequency and Amplitude Modulation of Resting-State fMRI Signals and Their Functional Relevance in Normal Aging. Neurobiol. Aging 70:59-69 (2018). [Abstract]
Yang AC*, Tsai SJ, Lin CP, Peng CK. A Strategy to Reduce Bias of Entropy Estimates in Resting-State fMRI Signals. Front. Neurosci. 12:398 (2018). [PDF]
Xie W, Peng CK, Huang CC, Lin CP, Tsai SJ, Yang AC*. Functional brain lateralization in schizophrenia based on the variability of resting-state fMRI signal. Prog. Neuropsychopharmacol. Biol. Psychiatry26;86:114-121 (2018). [Abstract]
Huang CC, Yang AC, Chou KH, Liu ME, Fang SC, Chen CC, Tsai SJ, Lin CP. Nonlinear pattern of the emergence of white matter hyperintensity in healthy Han Chinese: an adult lifespan study. Neurobiol. Aging 67:99-107 (2018). [Abstract]
Ma Y, Shi W, Peng CK, Yang AC*. Nonlinear dynamical analysis of sleep electroencephalography using fractal and entropy approaches. Sleep Med. Rev.37: 85-93 (2018). [Abstract]
2017
Yang AC*, Tsai SJ. New Targets for Schizophrenia Treatment beyond the Dopamine Hypothesis. Int. J. Mol. Sci.18(8) (2017). [PDF]
Chang MC, Yang AC, Stanley HE, Peng CK. Measuring information-based energy and temperature of literary texts. Physica A. 468;783-789 (2017). [Abstract]
Lin WC, Shen CC, Tsai SJ, Yang AC*. Increased Risk of Myofascial Pain Syndrome Among Patients with Insomnia. Pain Med. 18(8):1557-1565 (2017). [Abstract]
2016
Hager B, Yang AC (Co-First Author), Brady R, Meda S, Clementz B, Pearlson GD, Sweeney JA, Tamminga C, Keshavan M. Neural complexity as a potential translational biomarker for psychosis. J. Affect. Disord.S0165-0327(16)30799-6 (2016). [Abstract]
Yang AC, Tsai SJ, Liu ME, Huang CC, Lin CP. The Association of Aging with White Matter Integrity and Functional Connectivity Hubs. Front. Aging Neurosci.15;8:143 (2016). [PDF]
Huang NE, Hu K, Yang AC, Chang HC, Jia D, Liang WK, Yeh JR, Kao CL, Juan CH, Peng CK, Meijer JH, Wang YH, Long SR, Wu Z. On Holo-Hilbert spectral analysis: a full informational spectral representation for nonlinear and non-stationary data. Philos Trans A Math Phys Eng Sci. 374:2065 (2016). [PDF]
Cheng W, Rolls ET, Qiu J, Liu W, Tang Y, Huang CC, Wang X, Zhang J, Lin W, Zheng L, Pu J, Tsai SJ, Yang AC, Lin CP, Wang F, Xie P, Feng J. Medial reward and lateral non-reward orbitofrontal cortex circuits change in opposite directions in depression. Brain 139(Pt 12):3296-3309 (2016). [Abstract]
Lan CC, Tsai SJ, Huang CC, Wang YH, Chen TR, Yeh HL, Liu ME, Lin CP, Yang AC*. Functional Connectivity Density Mapping of Depressive Symptoms and Loneliness in Non-Demented Elderly Male. Front. Aging Neurosci. 7:251 (2016) [Full text]
2015
Yang AC, Fuh JL, Huang NE, Shia BC, Wang SJ*. Patients with migraine are right about their perception of temperature as a trigger - time series analysis of headache diary data. J. Headache Pain 16:533 (2015). [Full text]
Ma Y, Dong M, Mita C, Sun S, Peng CK, Yang AC*. Publication Analysis on Insomnia: How Much Has Been Done in the Past Two Decades. Sleep Medicine 16(7):820-826 (2015). [Abstract]
Yang AC*, Hong CJ, Liou YJ, Huang KL, Huang CC, Liu ME, Lo MT, Huang NE, Peng CK, Lin CP, Tsai SJ. Decreased resting-state brain activity complexity in schizophrenia characterized by both increased regularity and randomness. Human Brain Mapping 36(6):2174-86 (2015). [Full text]
2014
Cheng CY, Yang AC, Huang CC, Liu ME, Liou YJ, Wu JC, Tsai SJ, Lin CP, Hong CJ. The Association of RAB18 Gene Polymorphism (rs3765133) with Cerebellar Volume in Healthy Adults. Cerebellum 13:616-22 (2014). [Abstract]
Tsai PJ, Chen SC, Hsu CY, Wu CW, Wu YC, Hung CS, Yang AC, Liu PY, Biswal B, Lin CP. Local awakening: Regional reorganizations of brain oscillations after sleep. Neuroimage 15;102 Pt 2:894-903 (2014). [Abstract]
Liang WK, Lo MT, Yang AC, Peng CK, Cheng SK, Tseng P, Juan CH. Revealing the brain's adaptability and the transcranial direct current stimulation facilitating effect in inhibitory control by multiscale entropy. Neuroimage 90; 218-34 (2014). [Abstract]
Wang EH, Yang AC*. Pisa syndrome after discontinuation of clotiapine in a patient with intractable insomnia. J. Clin. Psychopharmacol. 34;2:276-77 (2014). [Full text]
Yang AC, Huang CC, Liu ME, Liou YJ, Hong CJ, Lo MT, Huang NE, Peng CK, Lin CP, Tsai SJ*. The APOE ε4 allele affects complexity and functional connectivity of resting brain activity in healthy adults. Human Brain Mapping 35;7:3238-48 (2014). [Full text]
2013
Chung MS, Yang AC (co-first author), Lin YC, Lin CN, Chang FR, Shen SH, Ouyang WC, Loh EW, Chiu HJ*. Association of altered cardiac autonomic function with psychopathology and metabolic profiles in schizophrenia. Psychiatry Research 30;210(3):710-5 (2013). [Abstract]
Chen SP, Yang AC (co-first author), Fuh JL, Wang SJ. Autonomic dysfunction in reversible cerebral vasoconstriction syndromes. J. Headache Pain 25;14(1):94 (2013). [ Abstract ]
Shen CC, Tsai SJ, Perng CL, Kuo BIT, Yang AC*. Risk of Parkinson Disease Following Depression: A Nationwide Population-Based Study. Neurology 81(17):1538-44 (2013). [Abstract]
Yang AC, Wang SJ, Lai KL, Tsai CF, Yang CH, Hwang JP, Lo MT, Huang NE, Peng CK, Fuh JL*. Cognitive and neuropsychiatric correlates of EEG dynamic complexity in patients with Alzheimer’s disease. Prog. Neuropsychopharmacol. Biol. Psychiatry 47:52-61 (2013) [Abstract].
Wang EH, Yang AC* . Reversible skin rash in a bipolardisorder patient on first use of lithium. Psychiatry Clin. Neurosci. 67: 365 (2013). [Full text]
Lin YH, Ho YC, Lin SH, Yeh SH, Liu CY, Kuo TBJ, Yang CC, Yang AC* . On-Call Duty Effects on Sleep-State Physiological Stability in Male Medical Interns. PLoS ONE 8(6): e65072. [PDF]
Yang AC*, Tsai SJ. Is mental illness complex? From behavior to brain. Prog. Neuropsychopharmacol. Biol. Psychiatry 45:253-7 (2013). [Abstract]
Yang AC , Tsai SJ*. Complexity of mental illness: A new research dimension. Prog. Neuropsychopharmacol. Biol. Psychiatry 45:251-2 (2013). [PDF]
Ko FY, Yang AC , Tsai SJ, Zhou Y, Xu LM*. Physiologic and laboratory correlates of depression, anxiety, and poor sleep in liver cirrhosis. BMC Gastroenterology 13:18 (2013). [PDF]
Yang AC*, Yang CH, Hong CJ, Liou YJ, Shia BC, Peng CK, Huang NE, Tsai SJ. Effect of age, sex, index admission, and predominant polarity on the seasonality of acute admissions for bipolar disorder: a population-based study. Chronobiology International. 30(4):478-85 (2013). [Abstract]
Yang AC , Huang CC, Yeh HL, Liu ME, Hong CJ, Tu PC, Chen JF, Huang NE, Peng CK, Lin CP*, Tsai SJ*. Complexity of spontaneous BOLD activity in default mode network is correlated to cognitive Function in normal male elderly: a multiscale entropy analysis. Neurobiol. Aging 34(2):428-38 (2013). [PDF]
Yang AC*, Tsai SJ, Yang CH, Shia BC, Fuh JL, Wang SJ, Peng CK, Huang NE. Suicide and media reporting: a longitudinal and spatial analysis. Soc. Psychiatry Psychiatr. Epidemiol. 48(3):427- 35 (2013). [Abstract]
2012
Lan WH, Yang AC , Hwang JP, Hong CJ, Liou YJ, Yeh HL, Liu ME, Tsai SJ. Association of MTHFR C677T polymorphism with loneliness but not depression in cognitively normal elderly males . Neuroscience Letters 521(1):88-91 (2012). [Abstract]
2011
Yang AC* , Tsai SJ, Huang NE, Peng CK. Association of Internet search trends with suicide death in Taipei city, Taiwan, 2004-2009. J. Affect. Disord. 132:179-184 (2011). [PDF] Yang AC*, Tsai SJ*, Hong CJ, Wang C, Chen TJ, Liou YJ, Peng CK. Clustering heart rate dynamics is associated with β-adrenergic receptor polymorphisms: analysis by information-based similarity index. PLoS ONE 6(5): e19232 (2011 ). [PDF]
Chen SP, Fuh JL, Wang SJ, Tsai SJ, Hong CJ, Yang AC . Brain- derived neurotrophic factor gene Val66Met polymorphism modulates reversible cerebral vasoconstriction syndromes. PLoS ONE 6(3): e18024 (2011). [PDF]
Yang AC , Fuh JL, Huang NE, Peng CK, Wang SJ.* Temporal associations between weather and headache: analysis by empirical mode decomposition. PLoS ONE 6(1):e14612 (2011). [PDF]
Yang AC*, Tsai SJ, Yang CH, Kuo CH, Chen TJ, Hong CJ.* Reduced physiologic complexity is associated with poor sleep in patients with major depression and primary insomnia. J. Affect. Disord. 131:179-185 (2011 ). [PDF]
Yang AC*, Yang CH, Hong CJ, Tsai SH, Kuo CH, Peng CK, Mietus JE, Goldberger AL, Thomas RJ. Sleep state instabilities in major depression: detection and quantification with an Electrocardiogram-based spectrogram method. Psychophysiology 48 :285-291 (2011). [PDF]
Yang AC*, Tsai SJ, Huang NE. Decomposing the association of completed suicide with air pollution, weather, and unemployment data at different time scales. J. Affect. Disord. 129:275-281 (2011). [PDF]
2010
Yang AC*, Huang NE, Peng CK, Tsai SJ.* Do seasons have an influence on the incidence of depression? The use of an internet search engine query data as a proxy of human affect. PLoS ONE 5(10): e13728 (2010). [PDF]
Yang AC*, Tsai SJ, Yeh HL, Chen JY, Liou YJ, Huang JP, Hong CJ. Association of renal function and cognitive performance in elderly community-dwelling men without dementia. J. Am. Geriatr. Soc. 58(10) : 2046-8 (2010). [PDF]
Yang AC*, Hong CJ, Kuo CH , Chen TJ, Yang CH, Li C, Tsai SJ. Profiling objective sleep quality in a healthy Taiwanese sample using a novel electrocardiogram-based cardiopulmonary coupling analysis. Taiwanese Journal of Psychiatry, 24: 201-09 (2010). [PDF]
Yang AC , Hong CJ, Tsai SJ.* Heart rate variability in psychiatric disorders. Taiwanese Journal of Psychiatry 24:99-109 (2010). [PDF]
Yang AC*, Chen TJ, Tsai SJ, Hong CJ, Kuo CH, Yang CH, Kao KP.* BDNF Val66Met polymorphism alters sympathovagal balance in healthy subjects. Am. J. Med. Genet. B Neuropsychiatr. Genet.153B(5):1024-30 ( 2010) . [PDF]
2009
Cheng D, Tsai SJ, Hong CJ, Yang AC .* Reduced physiologic complexity of heart rate dynamics in healthy elderly men with APOE ε4 allele. PLoS ONE 4(11):e7733 (2009). [PDF]
2008
Yang AC*, Tsai SJ, Hong CJ , Hsieh CH, Liu ME, Yang CH. Association between heart rate variability and cognitive function in elderly community-dwelling men without dementia: a preliminary report. J. Am. Geriatr. Soc. 56(5):958-60 (2008). 2007
Peng CK*, Yang AC , Goldberger AL. Statistical physics approach to categorize biologic signals: from heart rate dynamics to DNA sequences. Chaos 17: 015115 (2007). [PDF]
2006
None
2005
Yang AC , Goldberger AL, Peng CK.* Genomic classification using an information-based similarity index: application to the SARS coronavirus. J. Comput. Biol. 12(8):1103-16 (2005). [PDF]
2004
Novak V*, Yang AC , Lepicovsky L, Goldberger AL, Lipsitz LA, Peng CK. Multimodal pressure-flow method to assess dynamics of cerebral autoregulation in stroke and hypertension. BioMedical Engineering Online 3:39 (2004). [PDF]
2003
Yang AC*, Hseu SS, Yien HW, Goldberger AL, Peng CK. Reply: Comment on Linguistic analysis of human heartbeats using frequency and rank order statistics. Physical Review Letters 92:109802 (2003). [PDF]
Yang AC*, Peng CK, Yien HW, Goldberger AL. Information categorization approach to literary authorship disputes. Physica A 329:473-483 ( 2003). [PDF]
Yang AC , Hseu SS, Yien HW*, Goldberger AL, Peng CK. Linguistic analysis of human heartbeats using frequency and rank order statistics. Physical Review Letters 90:108103 (2003). [PDF]
2002
Yang AC , Chang CH, Hseu SS, Yien HW* . Simulating healthy humans heart rate: a Markovian model. Computers in Cardiology 29:229-232 (2002). [PDF]
2001
Yang AC , Hseu SS, Yien HW*. Prediction of paroxysmal atrial fibrillation by footprint analysis. Computers in Cardiology 28:401-404 (2001). [PDF]